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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKG
All Species:
33.03
Human Site:
Y720
Identified Species:
60.56
UniProt:
P49619
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49619
NP_001074213.1
791
89096
Y720
A
M
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Chimpanzee
Pan troglodytes
XP_001152821
791
89168
Y720
A
M
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Rhesus Macaque
Macaca mulatta
XP_001092912
791
89195
Y720
A
M
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Dog
Lupus familis
XP_545239
790
88986
Y719
A
M
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WG7
788
88505
Y717
A
M
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Rat
Rattus norvegicus
P49620
788
88503
Y717
A
M
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
M631
T
L
Q
E
T
T
V
M
T
P
E
N
R
R
L
Chicken
Gallus gallus
XP_422650
933
102351
Y862
A
M
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696120
893
99287
Y822
A
I
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
R1143
C
L
H
M
G
Q
V
R
T
G
L
R
A
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
I721
S
A
M
Q
M
G
Q
I
K
A
G
V
R
G
A
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
S1151
D
L
M
F
A
R
Q
S
I
G
D
K
L
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
G662
P
L
P
V
Q
I
D
G
E
P
W
N
Q
Q
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
94
N.A.
89.7
88.2
N.A.
51.3
54.9
N.A.
59.2
N.A.
35.5
N.A.
46
38.3
Protein Similarity:
100
99.7
97.8
95.5
N.A.
94.1
93
N.A.
63.5
65.9
N.A.
72.7
N.A.
46.5
N.A.
63.2
48.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
93.3
N.A.
46.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
100
N.A.
100
N.A.
80
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
8
0
0
8
0
0
0
0
8
0
0
8
62
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
62
8
0
0
0
0
8
0
8
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
70
8
0
8
0
77
8
0
0
8
70
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
62
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
70
0
0
0
% K
% Leu:
0
31
0
0
0
0
0
0
0
0
70
0
8
8
8
% L
% Met:
0
54
16
70
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
16
0
0
0
0
8
% P
% Gln:
0
0
8
8
8
70
16
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
0
8
16
8
0
% R
% Ser:
8
0
0
0
0
0
0
8
0
0
0
0
62
8
0
% S
% Thr:
8
0
0
0
8
8
0
0
77
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
16
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _